RGS7G

RGS7G is not a widely recognized official gene symbol in major genomic databases as of mid-2024. The designation appears infrequently in informal sources or as a potential typographical variant and is not listed as an approved human gene name by standard nomenclature authorities. Because of this ambiguity, references to "RGS7G" should be checked against curated resources such as HGNC, NCBI Gene, Ensembl, or UniProt to determine the intended entity.

Related context: the RGS7 family (Regulator of G protein Signaling 7 and related proteins) is a well-characterized subgroup of RGS proteins. Members of this family typically act as GTPase-activating proteins for Gα subunits, accelerating termination of G protein-coupled receptor (GPCR) signaling. R7 family proteins commonly contain DEP and GGL domains, form obligate complexes with the atypical G protein subunit Gβ5, and are regulated by membrane-targeting partners such as R7BP. They are predominantly expressed in the nervous system and influence synaptic transmission, neuronal excitability, and behaviors linked to GPCR pathways.

If encountering "RGS7G" in a publication, dataset, or clinical report, users should verify whether it denotes RGS7, a paralog, an organism-specific annotation, a splice isoform, or an annotation error. Curation by authoritative genomic databases and consultation of original sources will clarify identity and functional information.