RAB7HEZ
Rab7hez is a protein that plays a crucial role in the endosomal sorting pathway, a process essential for the proper functioning of various cellular processes. It is a member of the Rab family of small GTPases, which are involved in the regulation of vesicular trafficking. Rab7hez is specifically localized to late endosomes and lysosomes, where it facilitates the sorting of cargo proteins and lipids for degradation or recycling.
The Rab7hez protein is encoded by the RAB7HEZ gene, which is located on chromosome 19 in humans.
Mutations in the RAB7HEZ gene have been linked to several genetic disorders, including Chediak-Higashi syndrome and
In summary, Rab7hez is a vital protein involved in the endosomal sorting pathway, with roles in cargo