Ptp3PTPN3
Ptp3PTPN3 refers to the gene and encoded protein known as protein tyrosine phosphatase non-receptor type 3 (PTPN3). In humans, PTPN3 encodes a cytoplasmic, non-receptor protein tyrosine phosphatase that is involved in removing phosphate groups from tyrosine residues on target proteins. This enzymatic activity serves to counteract tyrosine kinase signaling and helps regulate multiple cellular processes.
The PTPN3 protein typically features a catalytic phosphatase domain responsible for its enzymatic activity, along with
Functionally, PTPN3 participates in signaling pathways that govern cell adhesion, migration, and cytoskeletal organization. By dephosphorylating
Expression of PTPN3 has been detected in multiple tissues, with levels that can be modulated by developmental
In clinical and research settings, PTPN3 is studied for its potential roles in cancer and other disorders,