ProAir

ProAir is a brand name for inhaled albuterol, a short-acting beta-2 adrenergic agonist used to relieve and prevent bronchospasm in asthma and other reversible obstructive airway diseases. The ProAir line includes several inhalation products that deliver albuterol in different device formats, including a metered-dose inhaler (MDI) and dry powder inhalers, with a newer digital version available. Each inhalation typically delivers albuterol sulfate at about 90 micrograms per actuation, depending on the specific product.

ProAir HFA is a metered-dose inhaler that provides albuterol sulfate via a pressurized spray. ProAir Respiclick is a dry powder inhaler alternative, and ProAir Digihaler adds a built-in sensor to track inhaler usage. These devices are designed to provide rapid onset of relief from acute symptoms and to enable prevention of exercise-induced bronchospasm in appropriate patients.

Indications for ProAir include relief of acute bronchospasm and prevention of exercise-induced bronchospasm in individuals with asthma or other reversible airway conditions. Dosing is individualized and should follow a clinician’s instructions. Commonly, patients use two puffs as needed every 4-6 hours for relief, and two puffs 15 minutes before exercise to prevent EIB, though some regimens may vary.

Mechanism of action involves selective stimulation of beta-2 receptors in bronchial smooth muscle, leading to bronchodilation. Onset of relief typically occurs within minutes, with a duration of about 4-6 hours. Common adverse effects include tachycardia, palpitations, tremor, nervousness, throat irritation, and coughing. Patients should use the lowest effective dose and consult a healthcare provider for cardiovascular conditions or if symptoms worsen or do not improve.

See also: albuterol, other brand-name inhalers such as Ventolin and Proventil.