Platinumbased

Platinumbased refers to compounds or materials in which platinum is a central element. This includes coordination complexes, organometallics, alloys of platinum with other metals, and nanoparticles. Platinum is a member of the platinum group and is highly resistant to corrosion, with properties that make it useful across chemistry, medicine, and materials science.

Platinum-based chemotherapy drugs, notably cisplatin, carboplatin, and oxaliplatin, are among the most widely used anticancer agents. They work primarily by binding to DNA and forming intra- and interstrand crosslinks, which disrupt replication and transcription. While effective against many solid tumors, these drugs can cause nephrotoxicity, neurotoxicity, and bone marrow suppression, among other side effects. Research continues on improving selectivity, reducing toxicity, and overcoming resistance.

In catalysis and energy applications, platinum-based systems catalyze numerous reactions, including hydrogenation, dehydrogenation, hydrocarbon reforming, and fuel cell electrochemistry (notably the oxygen reduction reaction). Supported Pt catalysts (for example, Pt on carbon) are common in industry due to high activity and stability, although cost and susceptibility to poisoning by impurities are ongoing concerns.

In materials science and engineering, platinum and its alloys provide high strength, hardness, and corrosion resistance. Pt-based alloys with ruthenium, iridium, or copper are used in jewelry, electrical contacts, and corrosion-resistant coatings. Platinum is also used in thin films and plating for sensors, thermocouples, and catalytic surfaces.

Overall, the term platinumbased covers a broad range of platinum-containing systems whose properties derive from the distinctive chemistry of platinum and its ability to support catalytic activity, durable coordination, and medical efficacy.