Pileupbased
Pileup-based is a computational method used in bioinformatics to analyze next-generation sequencing data, particularly in the context of variant calling and genome assembly. The term "pileup" refers to the alignment of sequencing reads at a specific position in the genome, where multiple reads are stacked or "piled up" to provide information about the nucleotide composition at that site.
The pileup-based approach involves creating a pileup file, which is a text file that contains the aligned
One of the key advantages of the pileup-based method is its simplicity and efficiency. It allows for
Pileup-based methods are widely used in various applications, including cancer genomics, where they help identify somatic