Phenylisopropylamine

Phenylisopropylamine, also known as amphetamine, is a synthetic stimulant drug. It is a chiral molecule and exists as two enantiomers, dextroamphetamine and levoamphetamine, as well as the racemic mixture, amphetamine. Phenylisopropylamine acts as a central nervous system stimulant, increasing alertness and attention, and decreasing fatigue. It achieves this by increasing the levels of neurotransmitters like dopamine, norepinephrine, and serotonin in the brain.

Historically, amphetamine was first synthesized in 1887. It was later used medically for conditions such as narcolepsy, depression, and obesity. Its stimulant properties led to its use as a performance-enhancing drug by soldiers during World War II. However, due to its potential for abuse and addiction, its medical use has become more restricted.

Phenylisopropylamine is a controlled substance in many countries. Its illicit production and distribution are illegal. While medical formulations exist, their use is strictly regulated. The drug can be administered orally, nasally, or intravenously. Effects typically include increased heart rate, blood pressure, and respiration, as well as euphoria and a sense of increased energy. Potential side effects range from anxiety and insomnia to more severe cardiovascular issues and psychosis with prolonged or high-dose use.