Pex18p
Pex18p is a peroxin (peroxisomal biogenesis factor) in the budding yeast Saccharomyces cerevisiae. It is encoded by the PEX18 gene and functions as a membrane-associated co-receptor in the peroxisomal import pathway.
Pex18p participates in the import of proteins containing a type 2 peroxisomal targeting signal (PTS2). The PTS2
Localization and interactions are central to Pex18p’s role. Pex18p is a peroxisomal membrane protein that interacts
Biological significance and genetic observations indicate that Pex18p is essential for efficient PTS2-dependent import in yeast.
In summary, Pex18p is a yeast peroxisomal membrane co-receptor that collaborates with Pex7p and Pex21p to mediate