Perinjection

Perinjection refers to a method of administering medication or other substances directly into a specific area or tissue of the body. This approach is distinct from systemic administration, where a substance is introduced into the bloodstream and distributed throughout the entire body. Perinjection is often employed when a localized effect is desired, or when direct contact with the target site is crucial for efficacy.

Common examples of perinjection include intradermal injections, which are placed into the dermis layer of the skin, often used for allergy testing or smallpox vaccinations. Subcutaneous injections are delivered into the fatty tissue just beneath the skin, commonly used for insulin or certain vaccines. Intramuscular injections are administered into a muscle, allowing for faster absorption than subcutaneous injections and are used for a wide range of medications. Intra-articular injections target the joint space, frequently used for corticosteroids to treat inflammation. Intrathecal injections are delivered into the cerebrospinal fluid within the spinal canal, often for anesthesia or chemotherapy.

The specific technique, needle size, and volume of the injected substance depend on the target tissue and the purpose of the injection. Perinjection allows for a more concentrated delivery of medication to a particular area, potentially reducing systemic side effects and increasing therapeutic effectiveness at the site of administration. Medical professionals carefully select the appropriate injection site and method based on the patient's condition and the properties of the substance being administered.