Peptiids

Peptiids is not a standard term in established biochemistry or molecular biology. As of now, there is no widely accepted definition or classification under this name in mainstream literature. The word may appear as a typographical variant of related terms such as peptides or peptoids, or as a coined term in speculative or fictional contexts.

If used in some discussions, peptiids could be intended to denote a class of polymeric molecules that combine peptide-like features with non-peptide backbones or substituents, with the aim of improving properties such as proteolytic stability, bioavailability, or folding control. In many such discussions, ideas from existing families—such as peptoids (N-substituted glycines) and beta- or gamma-peptides, which explore alternative backbones to natural peptides—are used as reference points.

In hypothetical definitions, peptiids might exhibit diverse architectures, ranging from oligomeric chains that mimic natural peptides to more complex foldamers with defined secondary structures. Synthesis would likely involve solid-phase techniques and the incorporation of non-natural monomers, with purification relying on standard chromatographic methods.

Because the term lacks formal recognition, reported properties and applications are not standardized. If encountered in a specific source, it is essential to consult that work for the precise definition, scope, and examples. In the broader literature, researchers typically discuss peptides, peptoids, beta- and gamma-peptides, and other foldamer families rather than a unified category labeled “peptiids.”

See also: peptides; peptoids; foldamers; beta-peptides; gamma-peptides.