OrthoPhthalaldehyd

OrthoPhthalaldehyd, often abbreviated as OPA, is an organic chemical compound with the formula C8H6O2. It is a dialdehyde, meaning it possesses two aldehyde functional groups. In its pure form, OPA is a white to pale yellow crystalline solid. It is soluble in water and many organic solvents.

OPA is primarily known for its application as a high-level disinfectant, particularly in healthcare settings. Its effectiveness stems from its ability to cross-link proteins, which inactivates a wide range of microorganisms, including bacteria, viruses, fungi, and spores. OPA-based disinfectants are often used for sterilizing medical and dental equipment that cannot withstand autoclaving. A key advantage of OPA over some other disinfectants is its relatively low vapor pressure and less pungent odor compared to glutaraldehyde, another common disinfectant. However, OPA can stain skin and mucous membranes a dark color, and protective measures are necessary when handling it. It is also used in some industrial processes and as a reagent in analytical chemistry.