OpioidAgonistenersatztherapie

Opioid agonists are a class of drugs that bind to and activate opioid receptors in the body. These receptors are primarily involved in the perception of pain, but also play roles in mood, reward, and other physiological processes. When an opioid agonist binds to these receptors, it mimics the action of endogenous opioids, such as endorphins, leading to a range of effects.

The most well-known effect of opioid agonists is analgesia, or pain relief. This is achieved by reducing the transmission of pain signals from the body to the brain. Opioid agonists can also produce feelings of euphoria and well-being, which contributes to their potential for misuse and addiction. Other common side effects include respiratory depression, constipation, nausea, and sedation.

Opioid agonists are used in medicine for various purposes, including the management of moderate to severe pain, such as that associated with surgery or cancer. They are also used in the treatment of opioid use disorder, where they can help to reduce withdrawal symptoms and cravings. Examples of opioid agonists include morphine, oxycodone, hydrocodone, and fentanyl. Due to their potent effects and potential for dependence, opioid agonists are carefully controlled substances and require a prescription from a qualified healthcare professional. Their use is associated with significant risks, including overdose, which can be fatal.