Oncotic
Oncotic refers to the colloid osmotic pressure exerted by proteins, especially in blood plasma. The term is most often used to describe plasma oncotic (colloid osmotic) pressure, the pulling force that plasma proteins exert to draw water from the interstitial space back into capillaries. The primary protein responsible is albumin, which provides the major share of this force, with smaller contributions from globulins and other plasma proteins.
Physiologically, oncotic pressure helps maintain intravascular volume and facilitates the reabsorption of water from the interstitial
Typical values place plasma oncotic pressure at about 25–30 mmHg, whereas the interstitial oncotic pressure is
Clinical significance arises when plasma protein levels fall, as in hypoalbuminemia from liver disease, nephrotic syndrome,