NanoBecken

NanoBecken is a nanoscale analytical platform designed for selective capture and analysis of biomolecules in very small sample volumes. The core concept is a dense array of hollow, basin‑like nanostructures that provide high surface area and enclosed reaction spaces, enabling concentration and processing of single molecules or small molecular ensembles.

Each basin is fabricated from durable materials such as silicon nitride or graphene-based composites and is lined with a functional surface—antibody fragments, aptamers, or chemical ligands—chosen for target specificity. An integrated readout system using either electrochemical sensors, optical reporters, or plasmonic elements converts binding events into measurable signals. The design aims to minimize sample loss and cross‑talk between basins while allowing rapid exchange with the surrounding fluid.

Origins and status: NanoBecken emerged from a collaborative effort among nanotechnology researchers and was demonstrated in laboratory settings as a platform for multiplexed detection. Prototypes have shown sensitivity improvements over conventional microfluidic sensors in select assays and are being explored for point‑of‑care diagnostics as well as environmental monitoring.

Limitations and outlook: Challenges include scalable fabrication, robustness of surface functionalization, and integration with downstream data processing. While not yet a commercial product, NanoBecken is cited in research as a versatile nanostructured sensing platform with potential across biomedical and analytical chemistry applications.

See also nanofluidics and sensor arrays.