NREMbezogene

NREMbezogene is a term used in sleep science to describe phenomena, processes, or conditions that are related to non-rapid eye movement (NREM) sleep. The compound is commonly found in German-language literature but is used in some English texts to emphasize NREM-related aspects of sleep physiology or pathology. NREM sleep comprises stages N1 to N3, with slow-wave activity most prominent in N3 and characteristic features such as decreased sensory responsiveness and distinctive EEG patterns including sleep spindles and K-complexes.

NREM-related phenomena include normal features of NREM such as spindle activity, and clinical phenomena such as NREM parasomnias—somnambulism (sleepwalking), confusional arousals, and night terrors—typically arising from slow-wave sleep. These events are distinguished from REM-related phenomena, such as dream enactment and REM atonia loss, by their timing, EEG correlates, and associated autonomic changes.

Research into NREMbezogene phenomena relies on polysomnography to stage sleep and correlate symptoms with NREM stages, and on questionnaires and clinical interviews. The term helps researchers and clinicians categorize events that occur during non-REM sleep and may guide treatment strategies for parasomnias, sleep fragmentation, and disorders of arousal.

Some sources reserve the term for descriptive purposes in German texts, while others adopt it in multilingual reviews to reduce ambiguity between REM- and NREM-related sleep phenomena. Overall, NREMbezogene describes the subset of sleep-related processes particularly linked to non-REM sleep.