NDRG3

NDRG3, also known as N-myc downstream regulated gene 3, is a protein-coding gene found in humans. It is part of the NDRG gene family, which are known for their roles in cellular processes such as differentiation, stress response, and cancer. The NDRG3 protein is believed to function in regulating cell growth and survival. Research suggests that NDRG3 may act as a tumor suppressor in certain types of cancer, potentially by inhibiting cell proliferation and promoting apoptosis. Its expression levels have been observed to be altered in various cancers, including colorectal, breast, and lung cancer, hinting at its involvement in tumorigenesis. The precise molecular mechanisms by which NDRG3 exerts its functions are still under investigation, but it is thought to interact with other proteins involved in signaling pathways. Further research is ongoing to fully elucidate the biological significance of NDRG3 and its potential as a therapeutic target in cancer treatment.