Multistapsyntheses
Multistapsyntheses is a concept in synthetic chemistry that describes constructing complex target molecules by assembling them through multiple modular stages. Each stage uses standardized building blocks and reaction motifs to enable reuse and rapid diversification.
Core ideas include modularity, standard connectors, and iterative design. Planning often relies on retrosynthetic analysis and
In practice, the workflow emphasizes compatibility of conditions across stages, minimal protection-deprotection steps, and the potential
Benefits include higher throughput, easier optimization, better scalability, and the ability to rapidly generate libraries of
Applications include drug discovery, natural product synthesis, materials science, and polymers. Future directions involve integration with
See also: multistage synthesis, modular synthesis, automated synthesis.