MtBl
MtBl, also known as Methylenetetrahydrofolate Reductase, is an enzyme encoded by the MTHFR gene in humans. This enzyme plays a crucial role in the folate metabolism pathway. Specifically, MtBl catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate. This process is essential for the remethylation of homocysteine to methionine. Methionine is an amino acid vital for numerous bodily functions, including DNA synthesis, repair, and methylation.
Variations in the MTHFR gene, commonly referred to as MTHFR polymorphisms or mutations, can lead to reduced