Mikrobubbelkontrast

Mikrobubbelkontrast refers to the use of tiny gas bubbles as a contrast agent in medical ultrasound imaging. These microbubbles are typically filled with a gas that is less soluble in blood than air, such as perfluorocarbon gases. When injected into the bloodstream, these bubbles reflect ultrasound waves more effectively than blood alone, thereby enhancing the visibility of blood vessels and tissues.

The size of these microbubbles is crucial, generally ranging from 1 to 10 micrometers in diameter, allowing them to pass through the smallest capillaries. This size is significantly larger than red blood cells. The contrast enhancement arises from the acoustic impedance mismatch between the bubble's gas core and the surrounding biological tissues. When the ultrasound waves interact with these bubbles, they cause them to vibrate, scatter, and resonate at specific frequencies. This scattered ultrasound energy is detected by the transducer, creating a brighter signal on the ultrasound image.

Mikrobubbelkontrast agents are primarily used to improve the visualization of blood flow in various organs, aiding in the diagnosis of conditions such as liver tumors, cardiac abnormalities, and vascular diseases. They are particularly useful in situations where traditional contrast agents might be contraindicated due to kidney issues or allergies. The bubbles are designed to be cleared from the body naturally, usually through exhalation, making them a safe option for many patients. Their use represents a significant advancement in ultrasound technology, offering a non-invasive method for detailed vascular imaging.