MayGrünwaldLösung

MayGrünwaldLösung, also known as May-Grunwald-Giemsa stain, is a histological staining method used to visualize cells and tissue structures. Developed in 1890 by Richard von May and Ernst Gimens, it is a tried and trusted technique in cytological and histological examinations.

The stain, a modification of the Giemsa stain, is a mixture of Trypan blue, Eosin Y, and Formaldehyde, which stains cell nuclei blue, metaphases red, and cytoplasm pink. The combination of these dyes provides a high level of detail in cell morphology, and the substitution of dyes in May-GrÄnwald stain has a proven inhibitory effect on glycogen, xanthine, and histidine, increasing the effectiveness of the staining process.

The applications of MayGrünwaldLösung are vast, ranging from the staining of fixed peripheral blood cells to cell cultures and tissue sections. The procedure is broadly utilized in parasitological examinations for the identification of protozoa and also as a complementary method for the determination of cell lineage anomalies.

Laboratory personnel commonly use May-GrünwaldGiemsa stain to diagnose infectious diseases such as malaria. This versatile and multi-faceted application has been widely used throughout the years for biopsies and samples from patients with various types of diseases. Along with Hematoxylin & Eosin (HE) staining techniques, May-Grünwald has firmly established its place as a viable and effective method of analyzing tissues and cells.