MRFV

MRFV, which stands for Mouse Respirovirus, is a species of paramyxovirus that infects mice. It is a member of the genus Respirovirus, which also includes viruses that infect rats and humans. MRFV is known to cause respiratory disease in mice, often manifesting as sneezing, coughing, and nasal discharge. In some cases, more severe symptoms such as lethargy and weight loss can occur. The virus is highly contagious and spreads through respiratory droplets.

MRFV is a significant concern in laboratory animal settings where it can impact the health and welfare of research mice, potentially confounding experimental results. Strict biosecurity measures and regular monitoring are employed in animal facilities to prevent the introduction and spread of MRFV. Diagnosis is typically made through serological tests or by detecting viral RNA in respiratory samples. While there is no specific treatment for MRFV infection, supportive care can help alleviate symptoms in affected animals. Prevention through maintaining specific pathogen-free (SPF) status in animal colonies is the primary strategy for controlling MRFV. Understanding the transmission dynamics and pathogenesis of MRFV is crucial for effective management and control in research environments.