Lümfoplasmotsüüdidest

Lümfoplasmotsüüdidest is a term referring to lymphocytes that exhibit features of both lymphocytes and plasma cells. These cells are typically found in reactive lymphoid tissue and are involved in the immune response. Morphologically, lümfoplasmotsüüdid possess a variable appearance. They may have a round or oval nucleus with condensed chromatin, similar to a lymphocyte, but often with a more eccentric location. The cytoplasm can range from scant to moderate, and it may show basophilia, indicating the presence of ribosomes involved in protein synthesis, a characteristic of plasma cells. Furthermore, some lümfoplasmotsüüdid might display a perinuclear halo, a pale area adjacent to the nucleus, which is also a feature of mature plasma cells. These cells are generally considered to be part of a transitional stage in the differentiation of B lymphocytes into antibody-producing plasma cells. Their presence is often associated with inflammatory or infectious conditions, as well as certain immunological disorders. Histologically, they are observed in various tissues, including lymph nodes, spleen, and bone marrow. The exact significance and role of lümfoplasmotsüüdid can vary depending on the clinical context and the specific location where they are found. They are an important indicator of cellular immune activity.