Kupplungsreaktionen
Kupplungsreaktionen are a vital class of organic chemical reactions where two molecular fragments are joined together by forming a new carbon-carbon bond. These reactions are often catalyzed by transition metals, such as palladium, nickel, or copper, which play a crucial role in facilitating the bond formation. The process typically involves the activation of one or both coupling partners, followed by their association and subsequent reductive elimination to yield the desired coupled product and regenerate the catalyst.
A common feature of many Kupplungsreaktionen is the use of organometallic reagents, such as organoboranes (in
The development of Kupplungsreaktionen has revolutionized organic synthesis, providing efficient and selective methods for constructing carbon-carbon