Korrelmiddel

Korrelmiddel is a term used in several industries for substances that promote the formation and stability of granules or pellets in powdery materials. It is not a single chemical, but a category of processing aids or excipients that influence the size, shape, flow, and integrity of granules formed during processing.

In pharmaceutical manufacturing, korrelmiddelen are used to produce uniform granules during granulation. Their roles include binding particles together during wet granulation, aiding drying and hardening of granules, and sometimes acting as disintegrants or lubricants depending on the formulation. The choice of korrelmiddel affects granule size distribution, density, porosity, and tablet hardness.

In the food and feed industries, korrelmiddelen help form granules or pellets to improve handling, mixing, and texture. They can reduce dust, improve flow, and support consistent portioning. In agriculture, granulation of fertilizers or seeds often relies on korrelmiddelen to achieve uniform pellet size and controlled release characteristics.

Common considerations when selecting a korrelmiddel include compatibility with active ingredients, processing temperature and humidity, regulatory status, and safety. The goal is to obtain granules with desired mechanical properties, stability, and performance in the final product. Different granulation methods exist, such as wet granulation, dry granulation, spray granulation, and extrusion-spheronization, and the chosen method influences the properties of the resulting granules.

Overall, korrelmiddelen are processing aids that enable controlled formation of granules, improving handling, dosing accuracy, and product performance across multiple industries.