Komplementdefekte
Komplementdefekte, also known as complement deficiencies, are a group of rare genetic disorders characterized by the absence or dysfunction of components of the complement system. The complement system is a part of the immune system that plays a crucial role in the body's defense against infections and other foreign invaders. It consists of a series of proteins that work together to enhance the immune response.
There are several types of komplementdefekte, each resulting from a deficiency in a specific complement component.
1. C1q deficiency: This is the most common type, affecting about 1 in 200 people. It is
2. C1r/C1s deficiency: This is a rare disorder that can cause recurrent infections, particularly of the skin
3. C2 deficiency: This can lead to recurrent infections, particularly of the skin and soft tissues, as
4. C3 deficiency: This is a severe disorder that can lead to recurrent infections, particularly of the
5. C4 deficiency: This can lead to recurrent infections, particularly of the skin and soft tissues, as
6. C5 deficiency: This is a rare disorder that can lead to recurrent infections, particularly of the
7. C6 deficiency: This is a rare disorder that can lead to recurrent infections, particularly of the
8. C7 deficiency: This is a rare disorder that can lead to recurrent infections, particularly of the
9. C8 deficiency: This is a rare disorder that can lead to recurrent infections, particularly of the
10. C9 deficiency: This is a rare disorder that can lead to recurrent infections, particularly of the
Komplementdefekte are typically inherited in an autosomal recessive pattern, meaning that a person must inherit the
Treatment for komplementdefekte varies depending on the specific type and severity of the disorder. In some