Klorheksidiini

Klorheksidiini is a synthetic antibiotic belonging to the fluoroquinolone class. It is used to treat a variety of bacterial infections, including respiratory tract infections, urinary tract infections, and skin and soft tissue infections. Klorheksidiini works by inhibiting the DNA gyrase enzyme, which is essential for bacterial DNA replication and repair.

The drug is available in various forms, including tablets, oral suspensions, and injectable solutions. It is typically administered orally, but intravenous administration is also possible for severe infections. Klorheksidiini is generally well-tolerated, but like all antibiotics, it can cause side effects. Common side effects include gastrointestinal disturbances, such as nausea, vomiting, and diarrhea. Less common but more serious side effects may include tendon rupture, which is a rare but serious condition that can occur with the use of fluoroquinolones.

Klorheksidiini is contraindicated in patients with a history of tendon rupture or severe liver disease. It should be used with caution in patients with kidney disease, as it can be excreted by the kidneys and may accumulate in patients with impaired renal function. Pregnant women should avoid klorheksidiini unless absolutely necessary, as it can potentially harm the developing fetus.

The use of klorheksidiini should be guided by a healthcare professional, who will consider the specific infection, the patient's medical history, and potential side effects. It is important to complete the full course of treatment, even if symptoms improve, to ensure the infection is fully eradicated.