Kgluconate

Potassium gluconate, also written as K-gluconate, is the potassium salt of gluconic acid. Its chemical formula is C6H11KO7. It is used primarily as a source of potassium for dietary supplementation and to treat or prevent potassium deficiency. In medical contexts, potassium gluconate may be chosen over other potassium salts when chloride load should be minimized or when a certain taste profile is preferred.

Forms and administration: Potassium gluconate is available in oral forms such as tablets, capsules, and powders, and in some intravenous solutions for clinical use. Oral forms are common as over-the-counter supplements to address mild potassium deficits, while intravenous forms are used in medical settings under supervision to replenish potassium more rapidly.

Pharmacology: Potassium is an essential intracellular cation involved in nerve conduction, muscle contraction, heart rhythm, and fluid balance. When ingested or administered, potassium gluconate dissociates to release potassium ions, which are absorbed primarily from the small intestine and then distributed to body stores and excreted by the kidneys.

Safety and precautions: The main risk of potassium gluconate is hyperkalemia, especially in people with kidney impairment, those taking medications that increase potassium (such as ACE inhibitors, ARBs, or potassium-sparing diuretics), or in cases of dehydration. Gastrointestinal irritation can occur with oral forms. Potassium supplementation should be guided by healthcare providers in individuals with kidney disease, cardiac conditions, or other conditions affecting potassium balance.

Regulation and notes: Potassium gluconate is marketed as a dietary supplement in many regions and is not a substitute for prescribed therapy in cases of significant potassium deficiency. Follow dosing instructions and medical guidance, particularly when coexisting medical conditions or medications are present.