KdT

KdT is an acronym or symbol without a single, universally accepted meaning. In scientific writing, Kd is commonly used for the dissociation constant of a binding reaction, while T denotes temperature. When used together as Kd(T) or KdT, the expression typically signals that the dissociation constant is being considered as a function of temperature rather than a fixed value. However, the exact sense of KdT depends on the context and the author’s conventions.

In chemistry and biochemistry, the dissociation constant Kd describes the affinity between a ligand and a target, with smaller Kd indicating tighter binding. Kd(T) emphasizes how binding affinity changes with temperature. The temperature dependence can be analyzed using the van’t Hoff equation, which relates changes in Kd to the enthalpy of binding and to temperature.

Outside of chemistry, KdT may appear as an internal code, project name, or shorthand in notes, where its meaning is defined locally by the author or organization. Because there is no standard definition, readers should interpret KdT from the surrounding text.

Related terms include Kd, the dissociation constant, and general discussions of temperature dependence in binding reactions. The term KD-tree, while similarly composed, is a separate concept in computer science and is not equivalent to KdT.