Kapselsynthese

Kapselsynthese refers to the process of synthesizing or producing capsules, typically in the pharmaceutical, nutraceutical, or food supplement industries. The term is derived from the German words *Kapsel* (capsule) and *Synthese* (synthesis), indicating a manufacturing approach that combines materials to form encapsulated dosage forms. Capsules are hollow shells, usually made from gelatin or synthetic polymers, designed to contain active ingredients such as drugs, vitamins, or herbal extracts.

The primary goal of kapselsynthese is to create uniform, stable, and easily administrable dosage forms. Gelatin capsules, the most common type, are made from collagen derived from animal sources, while vegetarian or vegan alternatives use materials like hypromellose (HPMC) or pullulan. The manufacturing process involves filling the pre-formed shells with powdered, granular, or liquid contents, followed by sealing to ensure the contents remain protected until consumption.

Key considerations in kapselsynthese include capsule size, fill weight, and compatibility between the shell material and the active ingredient. Factors such as moisture sensitivity, stability, and dissolution rate must also be addressed to ensure the product maintains efficacy throughout its shelf life. Automation and precision equipment are often employed to achieve consistency in production, particularly in large-scale manufacturing.

Beyond pharmaceuticals, kapselsynthese is applied in dietary supplements and functional foods, where capsules provide a convenient way to encapsulate sensitive or unpalatable substances. The process adheres to strict regulatory standards to ensure safety, quality, and compliance with industry guidelines. Advances in materials science continue to expand the possibilities for capsule formulations, including time-release and targeted delivery systems.