JMY

JMY is an acronym that can refer to more than one entity, with its most widely cited use in biology. In this context, JMY denotes a human gene that encodes a multifunctional protein involved in transcriptional regulation and actin cytoskeleton dynamics. The JMY protein has been described as a cofactor for the tumor suppressor p53, capable of enhancing p53-dependent transcription in response to DNA damage, and as an actin nucleation factor that promotes polymerization of actin filaments through interactions with Arp2/3 and WH2-domain motifs. The gene is expressed in multiple tissues, and its activity is associated with cellular stress responses and, in some studies, cancer-related pathways. Ongoing research aims to clarify how JMY coordinates transcriptional activation with cytoskeletal remodeling and how alterations in its expression or function may contribute to disease.

Outside of biology, JMY is also used as an acronym or identifier in other contexts, including institutions, projects, or products in various fields. The intended meaning in any given document is typically clarified by surrounding text or additional identifiers. In a comprehensive reference, a disambiguation would list the different uses of JMY and direct readers to the appropriate topic based on context.