Inodilators
Inodilators are a class of pharmacological agents that simultaneously exert positive inotropic and vasodilatory effects on the cardiovascular system. They are used primarily in the management of heart failure and other conditions characterized by impaired cardiac function and reduced systemic vascular resistance. The dual mechanism of action allows inodilators to improve cardiac output while reducing afterload, thereby enhancing myocardial efficiency.
The most well-known inodilator is milrinone, a phosphodiesterase-3 (PDE-3) inhibitor. By inhibiting PDE-3, milrinone increases intracellular
Inodilators are particularly useful in patients with acute decompensated heart failure, where rapid hemodynamic improvement is
The selection of an inodilator depends on individual patient factors, including the underlying cause of heart