Immunstatusbewertungen

Immunstatusbewertungen, also known as immune status assessments or immunological evaluations, are systematic medical procedures designed to evaluate the functionality and components of an individual's immune system. These assessments are crucial for diagnosing immunodeficiencies, monitoring the effectiveness of treatments, and understanding an individual's susceptibility to infections.

The process typically involves a combination of clinical history, physical examination, and laboratory tests. Clinical history may inquire about recurrent or unusual infections, allergies, autoimmune conditions, and family history of immune disorders. Physical examination might focus on signs like enlarged lymph nodes or skin conditions associated with immune dysfunction.

Laboratory tests form the cornerstone of immunstatusbewertungen. These can include a complete blood count (CBC) to assess the number and types of white blood cells, which are key players in the immune response. Further tests may involve quantifying specific immune cells like T-cells, B-cells, and natural killer cells using flow cytometry. Antibody levels, including immunoglobulins (IgG, IgA, IgM), are often measured to assess the humoral immune response. Additionally, functional assays can be performed to evaluate the ability of immune cells to perform their tasks, such as phagocytosis by neutrophils or T-cell proliferation in response to stimulants.

The results of an immunstatusbewertung help clinicians identify a wide range of conditions, from primary immunodeficiencies (genetic disorders) to secondary immunodeficiencies caused by factors like HIV infection, certain medications, or chronic diseases. Based on the findings, appropriate treatment strategies can be implemented, which might include immunoglobulin replacement therapy, prophylactic antibiotics, or other targeted interventions to bolster immune function and prevent infections.