Immunofenotípusának

Immunofenotípusának is a term used in immunology to describe the characteristic set of proteins or antigens expressed on the surface of a cell or within a cell, which can be detected by specific antibodies. This unique profile helps to identify and differentiate various cell types, particularly immune cells like lymphocytes, monocytes, and granulocytes.

The immunophenotype of a cell is determined by its genetic makeup and its stage of development and activation. For example, different types of T cells, such as helper T cells and cytotoxic T cells, express distinct surface markers that define their function. Similarly, B cells and plasma cells have unique immunophenotypic profiles.

Analyzing the immunophenotype is crucial for diagnosing and monitoring various diseases, especially hematological malignancies like leukemia and lymphoma. By identifying abnormal immunophenotypic patterns, clinicians can determine the specific type of cancer, its aggressiveness, and track its response to treatment. Flow cytometry is a common technique used to assess immunophenotype, allowing for the rapid analysis of multiple cell populations and their marker expression. This information is vital for making informed clinical decisions and developing personalized treatment strategies.