Iminebased

Iminebased describes chemical systems, materials, or reactions in which the imine functional group plays a central role. An imine is a carbon–nitrogen double bond (C=N) typically formed by the condensation of a primary amine with a carbonyl compound such as an aldehyde or ketone, with water released as a byproduct. Imines are generally electrophilic at the carbon of the C=N bond and can be hydrolyzed back to the corresponding amine and carbonyl under aqueous conditions; their stability depends on substituents, solvent, and pH.

In organic synthesis and catalysis, imine-based chemistry encompasses the use of imines and related species as reactive intermediates. Iminium ions, generated from imines under acid catalysis, act as electrophilic activators for nucleophilic additions in enantioselective transformations. Transimination processes allow exchange of imine partners, enabling dynamic combinatorial approaches and reversible tag-and-release strategies in synthesis and materials design.

In materials science, imine-based polymers and networks—often called polyimines—form through condensation of diamines with dialdehydes to create dynamic covalent bonds. These polyimine networks can exhibit self-healing, recyclability, and tunable mechanical properties through imine exchange. Their hydrolytic sensitivity can be a feature for degradable materials and recyclability, but it also imposes moisture- and pH-dependent stability constraints.

In coordination chemistry and catalysis, imine-based ligands (Schiff bases) coordinate metals and serve as platforms for various catalytic and functional materials. They offer structural versatility and tunable electronic properties through modification of the imine linkage and attached substituents.

Overall, iminebased describes a broad landscape where imine linkages drive reactivity, structure, and function across chemistry and materials science.