HomBC
HomBC is a two-subunit protein complex identified in bacteria, comprising HomB and HomC. The name reflects its putative involvement in homologous recombination and DNA repair pathways, as suggested by genomic context and sequence similarity to related factors.
Discovery of HomBC stems from comparative genomics and protein-interaction screens that repeatedly associate HomB and HomC
Functionally, HomBC is hypothesized to participate in processing recombination intermediates or stabilizing stalled replication forks, with
Genomic distribution of homBC varies among bacteria; the genes are often part of a broader DNA metabolism
Current knowledge is limited to bioinformatic predictions and sparse biochemical data. No high-resolution structures or widely