HeckReaktionen
HeckReaktionen, also known as the Heck reaction, is a palladium-catalyzed chemical process used in organic chemistry to form carbon-carbon bonds. This reaction involves the coupling of alkenes with halogenated aromatic compounds, such as aryl or vinyl halides, under specific conditions. Developed independently by Richard F. Heck in the 1960s, the reaction has become a fundamental tool in the synthesis of complex organic molecules, including pharmaceuticals, agrochemicals, and materials science compounds.
The general mechanism involves the oxidative addition of the halogenated aromatic compound to a palladium(0) catalyst,
The reaction is notable for its regioselectivity and the ability to tolerate a wide range of functional
Due to its efficiency and selectivity, the Heck reaction is regarded as a cornerstone in modern organic