HLAösszeillesztés
HLA matching, also known as Human Leukocyte Antigen (HLA) matching, is a process used in transplantation medicine to identify compatible donors for organ or bone marrow transplants. The HLA system is a set of genes located on chromosome 6 that encode proteins found on the surface of cells. These proteins play a crucial role in the immune system's ability to distinguish between self and non-self cells. In transplantation, HLA matching is essential because the immune system of the recipient may attack the transplanted organ or bone marrow if it recognizes it as foreign.
The HLA system is highly polymorphic, meaning there are many different versions of the HLA genes. The
HLA matching is typically performed using molecular techniques such as polymerase chain reaction (PCR) and sequencing.
The goal of HLA matching is to minimize the risk of graft rejection, which occurs when the