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H2O2Plasmasterilisation

H2O2Plasmasterilisation is a sterilization technology that combines hydrogen peroxide chemistry with a plasma phase to inactivate microorganisms on heat-sensitive medical devices and other equipment. In this method, hydrogen peroxide is introduced into a sealed chamber as vapor or gas. An energy source, such as radiofrequency or microwave power, generates a plasma, producing reactive species that attack microbial cells, proteins, and nucleic acids. The process operates at relatively low temperatures, reducing the risk of damage to sensitive items. After the biocidal phase, residual hydrogen peroxide is broken down by the plasma or during an aeration step, leaving the load with minimal residues.

The process typically involves loading devices into a sterilization chamber, conditioning the load, introducing hydrogen peroxide

Advantages of this approach include effective sterilization at low temperature, relatively rapid cycles, and good material

Applications are common in healthcare settings for sterilizing medical devices such as surgical instruments, endoscopes, catheters,

gas,
generating
plasma
to
activate
the
sterilant,
maintaining
a
sterilization
dwell
time,
and
then
venting
or
aerating
to
remove
residual
hydrogen
peroxide.
The
efficacy
depends
on
the
chamber
design,
gas
distribution,
and
cycle
parameters.
Materials
compatibility
varies;
some
plastics,
elastomers,
and
coatings
may
tolerate
the
process
differently,
and
lumens
or
complex
channels
can
affect
penetration.
Proper
aeration
and
verification
are
essential
to
ensure
safety
and
performance.
compatibility
for
many
heat-
and
moisture-sensitive
items.
The
technology
also
leaves
minimal
residues,
as
hydrogen
peroxide
breaks
down
into
water
and
oxygen.
Limitations
include
the
need
for
validated
equipment
and
protocols,
potential
compatibility
issues
with
certain
materials,
and
adherence
to
safety
and
regulatory
guidelines
for
hydrogen
peroxide
vapors
and
plasma
generation.
and
other
sensitive
equipment,
with
ongoing
evaluation
in
hospital
decontamination
workflows.