FtsKSpoIIIE
FtsKSpoIIIE is a proposed DNA translocase concept that combines features of the bacterial division protein FtsK and the SpoIIIE family. In theoretical discussions it is described as an engineered fusion or hybrid protein that could coordinate chromosome movement with septum formation and, in sporulating cells, with forespore translocation.
Background: FtsK and SpoIIIE are hexameric ATPases that drive directional DNA translocation across division or sporulation
Proposed architecture: FtsKSpoIIIE would ideally combine an N-terminal localization domain derived from divisome-associated proteins with a
Function and implications: In theory, the protein could localize to the division septum in vegetative cells
Notes: FtsKSpoIIIE is not a confirmed natural protein and is mainly discussed in speculative or synthetic biology