Fibrinogenbestand

Fibrinogenbestand refers to the concentration of fibrinogen in a biological sample, typically blood plasma. Fibrinogen is a soluble protein synthesized in the liver and is essential for blood clotting. It circulates in the plasma and, upon activation by thrombin, is converted into fibrin. Fibrin strands then polymerize to form a mesh that traps blood cells and platelets, leading to the formation of a blood clot.

Measuring fibrinogenbestand is a common laboratory test, often part of a coagulation panel, used to assess the body's ability to form clots. Elevated levels of fibrinogen can be indicative of inflammation, infection, or increased risk of thrombotic events. Conversely, low levels, known as hypofibrinogenemia or afibrinogenemia, can result from genetic disorders, liver disease, or disseminated intravascular coagulation (DIC), leading to an increased risk of bleeding.

The normal range for fibrinogenbestand in human plasma is typically between 200 and 400 milligrams per deciliter. However, these values can vary slightly depending on the laboratory and the specific assay used. The interpretation of fibrinogenbestand results should always be done in conjunction with other clinical findings and laboratory tests. This measurement is crucial in diagnosing and managing a variety of medical conditions.