ECMösszetevk
ECMösszetevk refer to the components of the extracellular matrix, a complex network of macromolecules that provides structural and biochemical support to surrounding cells in tissues. The ECM is produced by resident cells such as fibroblasts, chondrocytes, and epithelial cells, and its composition varies with tissue type and developmental stage. It influences cell adhesion, migration, proliferation, and differentiation and plays a central role in tissue mechanics.
Major components include fibrous proteins (collagens, elastin), proteoglycans and glycosaminoglycans (GAGs), and adhesive glycoproteins (fibronectin, laminin).
ECM functions include mechanical support, determination of tissue stiffness, and regulation of cell behavior through biochemical
Turnover and remodeling are dynamic, mediated by enzymes such as matrix metalloproteinases and tissue inhibitors of