Dupuytreni

Dupuytren disease, also known as Dupuytren contracture, is a progressive condition that affects the fascia, a layer of connective tissue beneath the skin of the palm and fingers. It is characterized by the formation of lumps and cords under the skin of the palm, which can eventually lead to a permanent bending or "contracture" of the fingers towards the palm. This contracture makes it difficult to fully extend the fingers, impacting grip strength and fine motor skills.

The exact cause of Dupuytren disease is unknown, but it is believed to have a genetic component and is more common in individuals of Northern European descent. It typically affects men more often than women and usually appears in middle age or later. Other factors that may increase the risk include smoking, alcohol consumption, diabetes, and certain medications.

Diagnosis is usually made through a physical examination, noting the characteristic lumps and cords in the palm and any resulting finger deformities. While there is no cure, treatment options aim to manage symptoms and prevent further progression. These can include observation for mild cases, needle aponeurotomy to break up the cords, collagenase injections to dissolve them, or surgical removal of the affected fascia. The choice of treatment depends on the severity of the contracture and its impact on daily function.