Dosisform

Dosisform is a term used in pharmacology and pharmacy to denote the dosage form of a drug product—the physical form in which an active pharmaceutical ingredient is supplied to a patient for administration. It encompasses a wide range of presentations, from solid forms such as tablets, capsules, and powders to liquids like solutions and suspensions, as well as semi-solid preparations such as creams and gels, and special forms including injectables, inhalable powders, transdermal patches, and implants. The dosisform is chosen to enable appropriate delivery of the drug dose by the intended route of administration.

The selection of a dosisform depends on factors such as the drug’s chemical properties, desired onset and duration of action, stability, patient population, and adherence considerations. Immediate-release forms aim for rapid onset, whereas extended-release or sustained-release forms modify absorption to prolong effect. The form also influences manufacturing, packaging, dosing accuracy, and storage requirements.

Development of a dosisform involves formulation design, selection of excipients, and consideration of stability, texture, taste, and compatibility with packaging. It must meet regulatory standards for quality, safety, and efficacy, including manufacturing under good manufacturing practices and appropriate release and stability testing. Quality attributes typically assessed include content uniformity, dissolution or release profile, sterility (where applicable), microbiological quality, and shelf life.

In practice, the term is closely related to the widely used concept of a dosage form, with variations in terminology across languages. See also dosage form, drug delivery, and pharmacokinetics.