DHHCfamilian

DHHCfamilian is a hypothetical biological term that does not correspond to any recognized gene, protein family, or scientific concept as of current scientific literature up to October 2023. It appears to be a fictional or misspelled reference, potentially intended to relate to the DHHC (aspartate-histidine-histidine-cysteine) family of proteins known for their role in palmitoylation, a post-translational modification involving the addition of fatty acids to proteins.

Proteins in the DHHC family are characterized by the presence of a conserved DHHC cysteine-rich motif within their structure. These enzymes primarily function as palmitoyl acyltransferases, catalyzing the reversible attachment of palmitic acid to cysteine residues on substrate proteins. This modification influences protein localization, stability, and interactions, and is crucial in cellular processes such as signaling, trafficking, and membrane dynamics.

The DHHC family is conserved across various species, from yeast to humans, highlighting its fundamental biological importance. In humans, there are 23 known DHHC enzymes, each with specific substrate preferences and cellular roles. Dysregulation of DHHC-mediated palmitoylation has been implicated in several diseases, including neurodegenerative disorders, cancer, and infectious diseases.

If "DHHCfamilian" refers to a specific or newly discovered entity outside current scientific consensus, additional context or sources would be necessary to provide accurate information. As it stands, "DHHCfamilian" does not match established scientific terminology and may require clarification or correction for accurate coverage.