Cytocompatibility
Cytocompatibility is a measure of how compatible a material or substance is with living cells. It describes the ability of the material to support cell survival, adhesion, proliferation and function while not causing cytotoxic effects. Cytocompatibility is a component of the broader concept of biocompatibility, focusing specifically on cellular responses to materials, surfaces, or extracts.
Assessment is typically performed in vitro using cell-based assays. Common approaches include direct contact tests and
Factors affecting cytocompatibility include material composition, surface chemistry, energy and wettability, roughness and topography, and the
Applications of cytocompatibility evaluation include medical implants, dental materials, tissue engineering scaffolds, and substrates for cell
In practice, regulatory and research contexts rely on standardized testing to compare materials and guide design