Chromans
Chromans are a class of heterocyclic organic compounds defined by a benzene ring fused to a saturated six-member oxygen-containing ring, giving a dihydrobenzopyran scaffold. The core is often described as 2H-1-benzopyran or chroman. In this context, the pyran ring is saturated at positions 2 and 3, in contrast to the unsaturated chromenes.
Chromans are related to other benzopyran families. Chromenes are the unsaturated congeners with a double bond
Chromans are encountered in natural products and are widely used as synthetic building blocks in medicinal
Chromans can be prepared by hydrogenation or cyclization approaches that incorporate a phenolic ring with a