Cellenbron

Cellenbron (literally "the cell bridge" in Swedish) is a descriptive term used in cell biology to refer to structures that create cytoplasmic connections between neighboring cells. It is not a formal taxonomic term but a label applied to various forms of intercellular bridges observed in different organisms, most notably tunneling nanotubes in animal cells and plasmodesmata in plant cells.

These bridges enable bidirectional transport of signaling molecules, ions and occasionally organelles such as mitochondria. Tunneling nanotubes are thin, actin-rich extensions that can span several micrometers and may be open or closed; plasmodesmata are permeability channels through plant cell walls; gap junctions provide another mode of coupling in animal tissues by allowing diffusion of small molecules between adjacent cells.

Function and significance include coordination during development, immune communication and tissue homeostasis. The concept of cellular bridges is also discussed in studies of cancer progression, neurodegenerative disease and wound healing. Some research indicates that intercellular bridges can facilitate the spread of signaling or, in some cases, pathogens, which presents both biological importance and therapeutic challenge.

Terminology and usage: the term "cellenbron" is more common in Swedish-language literature and conveys a broad concept rather than a single structural type; in international literature researchers typically refer to tunneling nanotubes, plasmodesmata, or gap junctions when describing specific structures.

See also: tunneling nanotubes; plasmodesmata; gap junctions.