Celestolide

Celestolide is a synthetic musk fragrance ingredient used in perfumery and various consumer products to impart a long-lasting musk odor. It was developed as part of the mid- to late-20th century expansion of artificial musk compounds and has since been employed in a wide range of scented formulations.

In perfumery and cosmetics, celestolide is valued for its durability and ability to anchor other fragrance notes. It is typically included at very low concentrations due to its potent odor, contributing a soft, warm, musky character to products such as perfumes, soaps, detergents, shampoos, and lotions. The compound is designed to be relatively stable within cosmetic matrices and to resist rapid evaporation, helping perfumes maintain their scent profile over time.

Safety and regulatory considerations surrounding celestolide include assessments of toxicology, irritation, and allergenicity. Overall acute toxicity is low, and irritation potential is generally limited, though rare cases of skin sensitization can occur with fragrance ingredients. Regulators have also evaluated the environmental persistence and potential for bioaccumulation of synthetic musks, leading to varying degrees of scrutiny and, in some markets, usage restrictions or concentration guidelines in consumer products. Companies typically provide safety data through standard channels, and celestolide is subject to cosmetics and chemical regulations in markets where fragrances are controlled.

See also: galaxolide, tonalide, musks in perfumery.