CYPentsyymeistä
CYPentsyymeistä, more commonly known as cytochrome P450 enzymes, is a superfamily of heme-containing enzymes found in all domains of life. In humans, these enzymes are primarily located in the liver, but they are also present in other tissues such as the intestines, lungs, and kidneys. The primary role of CYP enzymes is to catalyze the oxidation of a wide range of xenobiotic (foreign) compounds, as well as endogenous substances. This metabolic process is crucial for the detoxification and elimination of drugs, environmental toxins, and other harmful substances from the body.
CYP enzymes play a vital role in drug metabolism. They can activate prodrugs into their active forms,
Beyond drug metabolism, CYP enzymes are also involved in the synthesis of essential endogenous molecules. For