CYP450enzimrendszer
The CYP450 enzyme system, also known as cytochrome P450, is a superfamily of monooxygenase enzymes found in all domains of life. In humans and other mammals, these enzymes are primarily located in the liver, although they are also present in other tissues like the intestines, lungs, and kidneys. The primary role of CYP450 enzymes is to metabolize a wide range of endogenous compounds, such as steroids and fatty acids, as well as exogenous substances, including drugs, toxins, and environmental pollutants.
This metabolic process typically involves the addition of an oxygen atom to the substrate, often making it
The CYP450 system plays a critical role in pharmacology because it is responsible for the metabolism of